MTF Biologics – Innovation in Allograft Translational Research Grants (2026)
The Innovation in Allograft Translational Research Grants program from MTF Biologics supports high-impact translational and clinical research that advances allograft tissue science and improves patient outcomes. For 2026, MTF Biologics is seeking proposals that utilize allograft tissues or allograft-derived materials and demonstrate a clear, credible pathway to clinical translation.
Projects focused solely on autologous approaches, synthetic-only materials, or technologies not centered on allografts are out of scope.
Organization
MTF Biologics
Support Type
Research grants (translational and clinical research)
Geographic Focus
United States (academic and clinical research institutions)
About the Funder
MTF Biologics is a nonprofit organization dedicated to advancing tissue-based solutions that improve patient care. Through its research grant programs, MTF Biologics invests in scientific innovation that strengthens the clinical performance, safety, and value of allograft-based therapies across multiple surgical and regenerative medicine applications.
Clinical Areas of Interest
Proposed research may focus on, but is not limited to:
- Orthopaedics
- Plastic and reconstructive surgery
- Aesthetics
- Surgical soft-tissue repair
- Abdominal wall reconstruction
- Wound care
- Other specialties where allograft transplantation technologies can drive meaningful improvement
Topic Areas of Interest
MTF Biologics welcomes proposals aligned with the following areas:
- Novel allograft uses with defined translational strategies
- Combination approaches integrating allografts with biomaterials, biologics, or other modalities
- Allograft-centric technologies including advanced processing, preservation, activation, and decellularization/recellularization
- Tissue engineering and regenerative medicine using allografts as preferred platforms
- Real-world evidence and health economics, including outcomes and cost-effectiveness research
- Extracellular vesicles and secretome research derived from allograft tissues
- Computational and precision approaches, including AI/ML, genomics, donor profiling, and decision-support tools
Other innovative topics aligned with program objectives will also be considered.
Funding Tracks & Award Amounts
Qualified applicants may apply under one of the following tracks:
- Junior Investigator Award: One year, $75,000 (for investigators without prior major independent funding)
- Established Investigator Award: Three years, $225,000 (for investigators with prior major grant support)
- Career Development Award: Three years, $225,000 (for post-residency M.D. or D.O. applicants at an MTF Biologics Academic Member Institution)
Application Timeline
- Letters of Intent Due: March 23, 2026
- LOI Review & Invitation for Full Proposal: By end of April 2026
- Full Proposal Due (by invitation): June 15, 2026
- Awards Announced: By end of October 2026
Application Process
Applicants must first submit a Letter of Intent (LOI). Only applicants with positively reviewed LOIs will be invited to submit a full proposal. Full application requirements and review criteria are outlined in the official Request for Proposals.
Apply / Learn More
➡️ 2026 Innovation in Allograft Translational Research Grant RFP (PDF):
https://www.mtfbiologics.org/docs/default-source/grant-applications/2026/mtf-biologics-2026-innovation-grant-rfp.pdf?sfvrsn=d227a87d_3
Why This Opportunity Is a Good Fit
This program is an excellent fit for investigators developing translational or clinical research that advances allograft science with a clear path toward patient impact. It is particularly well suited for teams working at the intersection of tissue science, regenerative medicine, outcomes research, and clinically relevant innovation.
